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. 2017 Sep 25;1(2):259–263. doi: 10.1002/rth2.12046

Figure 1.

Figure 1

Effects of activated partial thromboplastin time (APTT) reagents, APTT reagent filtrates and contact activators on the activation of nonacog beta pegol (N9‐GP) and factor IX (FIX) (N9) during the clotting phase of a OS FIX clotting assay. The bars represent relative generation of activated factor IX (FIXa) activity in the presence of mere buffer (black), APTT reagent (red), APTT reagent filtrate (green), or isolated contact activator (purple). Striped and solid bars show the results obtained with N9 and N9‐GP, respectively. For each APTT reagent, the generation of FIXa activity was compared to that obtained using N9 in the presence of mere buffer (arbitrarily assigned the value 100%). The APTT reagents are indicated below the graph