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. 2018 Feb 27;25(1):690–702. doi: 10.1080/10717544.2018.1444684

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© 2018 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — (a–i) Response surface plots showed the effects of X₁(A), X₂(B) and X₃(C) on the response Y₁, Y₂ and Y₃. X₁ is the factor of concentration of PYM, X₂ is the factor of CS amount, X₃ is the factor of GP content, Y₁ is the response of cumulative release percentage of PYM in 1 day, Y₂ is the response of cumulative release percentage of PYM in 9 days, Y₃ is the response of rate constant k.