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Schematic representation of the rough PTX-PLGA-MS fabrication technique, tumor site injection and intracellular drug delivery pathway. Intracellular trafficking includes enhanced PTX uptake through adsorptive endocytosis, sustained PTX release, and promoted microtubule assembly and stabilization. The dysregulation of cell cycle progression includes arresting the G2/M cell phase and disturbing microtubules dynamic equilibrium.
