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In vivo simultaneous distribution in 4T1 metastasis model. In vivo targeting of CSOSA/DiR and TET-CSOSA/DiR to breast 4T1 tumor (A), dissected tumors and organs, (B) and quantification of the mean fluorescent intensity (C) after 48 h of injection (n = 3). (D) Fluorescence imaging of the dissected lungs after CSOSA/DiR and TET-CSOSA/DiR treatment in the 4T1 lung metastasis tumor bearing mice. ***p < .001.
