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. 2018 Apr 2;25(1):862–871. doi: 10.1080/10717544.2018.1425773

Figure 2.

Figure 2.

Optimization of CPs, cytotoxicity and uptake evaluation of CuB and CuB-MMs-CPs. The effects of CPs’ different molecular weight and quantity on Caco-2 intaking of CuB (A). Changes of amino acid ratio between before and after the separation of CPs (B). CuB release profiles from the micelles in vitro (C). Cytotoxicity of blank MMs-CPs, CuB, CuB-MMs, and CuB-MMs-CPs against HepG -2 cells (D, n = 3). Cellular uptake efficiency of the CuB, CuB-MMs, and CuB-MMs-CPs micelles by Caco-2 cells in different concentrations (12.5 μg/mL, 25 μg/mL, 50 μg/mL, 100 μg/mL, 200 μg/mL) or after 0.5 h, 1 h, 1.5 h, and 2 h incubation (E).