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. 2018 Apr 2;25(1):862–871. doi: 10.1080/10717544.2018.1425773

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© 2018 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — Transcellular transportation evaluation of CuB and CuB-MMs-CPs across the Caco-2 cell monolayer. The cumulative transport flux and transport rate of CuB and CuB-MMs-CPs from AP to BL and BL to AP (A and D). Effects of temperature on the transportation quantity of CuB and CuB-MMs-CPs across Caco-2 cell monolayers from AP to BL and BL to AP were investigated (B and E). The effect of efflux pump, ATP, and endocytosis inhibitors on the transportation of CuB and CuB-MMS-CPs were assayed (C and F).