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(a) The toxicity of the different-sized Ru@MSNs and RuPOP at 0.2 mg/kg on major organs after 21 d treatment. The scale bar is 100 μm. (b) Hematological analysis of healthy and tumor-bearing nude mice, and the treatment group of different-sized Ru@MSNs and RuPOP for 21 d. Value represents means ± SD (n = 3).
