Table 3.
The influence of hydrogels administration, on the number of RBC, WBC and platelets and on the GTP, GOT and LDH activity.
| RBC (×106/mm3) | WBC (×103/mm3) | Platelets (×103/mL) | GPT (U/mL) | GOT (U/mL) | LDH (U/L) | |
|---|---|---|---|---|---|---|
| Control | ||||||
| 24 h | 7.25 ± 2.7 | 8.18 ± 1.7 | 45.7 ± 1.9 | 85.2 ± 3.1 | 339.29 ± 37.21 | 318 ± 5.7 |
| 7 days | 7.43 ± 3.3 | 8.24 ± 1.9 | 47.8 ± 2.5 | 87.4 ± 2.3 | 341.47 ± 40.33 | 324 ± 4.9 |
| Chitosan | ||||||
| 24 h | 7.31 ± 1.2 | 8.15 ± 2.3 | 44.5 ± 2.3 | 87.8 ± 3.3 | 340.38 ± 36.39 | 311 ± 5.5 |
| 7 days | 7.46 ± 2.5 | 8.22 ± 2.7 | 49.3 ± 1.7 | 89.9 ± 1.9 | 343.51 ± 39.45 | 319 ± 6.7 |
| 5FU | ||||||
| 24 h | 9.34 ± 1.9** | 5.88 ± 1.5* | 51.3 ± 1.5 | 97.1 ± 2.5 | 344.26 ± 41.27 | 145 ± 6.5* |
| 7 days | 9.22 ± 3.2** | 5.63 ± 2.3* | 53.4 ± 2.7 | 97.9 ± 1.7 | 347.53 ± 37.51 | 140 ± 4.3* |
| CFU3 | ||||||
| 24 h | 9.35 ± 2.4** | 5.82 ± 1.5* | 55.6 ± 2,2 | 98.3 ± 3,5 | 343.17 ± 43.43 | 139 ± 5.5* |
| 7 days | 9.29 ± 2.7** | 5.75 ± 2.4* | 58.5 ± 1.9 | 98.7 ± 2.3 | 349.45 ± 38.29 | 135 ± 5.4* |
| CFU4 | ||||||
| 24 h | 9.33 ± 3.3** | 5.76 ± 2.2* | 53.9 ± 2.5 | 97.4 ± 1.7 | 345.39 ± 34.17 | 141 ± 4.2* |
| 7 days | 9.25 ± 2.3** | 5.68 ± 1.9* | 56.7 ± 1.7 | 98.2 ± 2.5 | 347.53 ± 38.25 | 137 ± 5.3* |
Values were expressed as mean ± SD.
*p < .05; **
p < .01 versus control for six mice in a group.