Table 3.
PK parameter | LCDP polymeric micelles | LCDP oral suspension | Statistical test |
---|---|---|---|
Cmax (ng/ml) | 230.68 ± 20.21 | 3.72 ± 1.55 | p = .000 |
tmax (h) a | 0.5 | 8 | p = .000 |
AUC(0–72) (ng h/ml) | 493.22 ± 67.28 | 69.59 ± 28.38 | p = .000 |
AUC(0–∞) (ng h/ml) | 498.87 ± 66.38 | 72.75 ± 26.97 | p = .000 |
λz (h−1) | 0.05 ± 0.01 | 0.05 ± 0.01 | p = .791 |
t1/2 (h) | 14.92 ± 3.21 | 15.02 ± 5.61 | p = .976 |
Median.