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Characterization of SFB-loaded polymeric nanoparticles.
| NPs | Dh (nm) | PDI | ZP (mV) | LC (%) | EE (%) |
|---|---|---|---|---|---|
| Null-NP | 95.3 ± 7.3 | 0.22 | –12.8 ± 0.6 | ||
| NP-SFB | 102.3 ± 6.3 | 0.15 | –14.1 ± 0.5 | 10.1 | 77.1 |
| NP-SFB-Ab | 115.1 ± 8.2 | 0.18 | –15.3 ± 0.8 | 9.9 | 75.9 |
Dh: average hydrodynamic diameter; PDI: polydispersity index; ZP: zeta potential; NP: TPGS-b-PCL/P123-Mal nanoparticles; SFB: sorafenib; LC: drug loading content; EE: drug encapsulation efficiency.
