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. 2018 Jul 18;9:1577. doi: 10.3389/fmicb.2018.01577

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Copyright © 2018 Turnbull and Douville.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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HMM logo of representative mature endogenous retrovirus K proteases. (A) The structure of the HIV-1 protease 3A2O (Hidaka et al., 2009) is shown with the major regions referenced in the text highlighted. (B) HMM logo of the aligned mature protease sequences of each ERVK entry in Repbase (HK1 through 10) with referenced regions highlighted in the same colors as the homologous regions in 3A2O. This figure was made with Pymol, Geneious, and GIMP.