Table 4.
Frequency of co-occurrence for observed ERVK active site and associated helix motifs.
| Number | B1 | C2 | Number | B1 | C2 | Number | B1 | C2 |
|---|---|---|---|---|---|---|---|---|
| Predicted active if translated | ||||||||
| 52 | DTGAD | GRDLL | 17 | DTGVD | GRDLL | |||
| Potentially active | ||||||||
| 4 | DTRAD | GRDLL | 1 | DTVVD | GRDLL | 1 | DTGDD | GRDLL |
| 4 | DTEAD | GRDLL | 1 | DTVAD | GRDLL | 1 | DTGAN | GRDLL |
| 3 | DTGSD | GRDLL | 1 | DTGVD | GRHLL | 1 | DTGAN | GKDLL |
| 3 | DTGED | GRDLL | 1 | DTGVD | GKDLL | 1 | DTGAD | GRELL |
| 3 | DTGAD | GQDLL | 1 | DTGTD | GRDLL | 1 | DTGAD | GRDIL |
| 3 | DTGAD | GKDLL | 1 | DTGMD | GRDLL | 1 | DTGAD | GQELL |
| 3 | DTDAD | GRDLL | 1 | DTGID | GRDLL | 1 | DTAAD | GRDLL |
| 2 | DTEVD | GRDLL | 1 | DTGGD | GRDLL | |||
| Predicted inactive if translated | ||||||||
| 4 | DTGAD | RRDLL | 1 | DTRSD | GRDLL | 1 | DTGAD | GHLL |
| 3 | DTGAD | ERDLL | 1 | DTRMD | GKEIY | 1 | DTEAD | GQDLL |
| 2 | HTGAD | GRDLL | 1 | DTRAD | GWDPL | 1 | DRGMD | GRDLL |
| 2 | DTVVD | GGTLL | 1 | DTGVD | LSPHTFI | 1 | DMGAD | DQDLL |
| 2 | WAWAV | GWDLL | 1 | DTGVA | GRDLL | 1 | DMGAD | |
| 1 | VTGVD | GRDLL | 1 | DTGPD | 1 | DIGVD | GRDLL | |
| 1 | ITWGR | GVDN | 1 | DTGVD | RRDLL | 1 | DIGAD | GGDLL |
| 1 | GWDLL | 1 | DTGAD | VWDLL | 1 | DIGAD | ERDLLL | |
| 1 | ETGVD | GWDLL | 1 | DTGAD | GVDLL | 1 | DAGAD | GRDLL |
| 1 | DTVAD | GGDLL | 1 | DTGAD | GTRPI | 1 | ATGAD | GRDLL |
| 1 | DTRTD | GRDVL | 1 | DTGAD | GRYLL | 1 | ALGAD | RRDLL |