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. 2018 Feb 22;103(6):1054–1064. doi: 10.3324/haematol.2017.178376

Figure 3.

Figure 3.

(+)-SW209415 accelerates neutrophil recovery after bone marrow transplantation (BMT) in mice treated with granulocyte colony-stimulating factor. Lethally irradiated (11 Gy) 8-week old female C57/BL6J mice were transplanted with 500×103 total bone marrow cells and treated with either vehicle, 2.5 mg/kg (+)-SW209415 (twice daily, intraperitoneally), 250 mg/kg human G-CSF (once daily, subcutaneously), or the combination. The graphs display the means and Standard Error of Mean of peripheral blood neutrophil counts on days 8, 12, and 18 after BMT and bone marrow SKL cell numbers determined in mice sacrificed on day 18 (13 mice/arm). *Student t-test P<0.05.