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. 2018 Mar 15;103(6):959–971. doi: 10.3324/haematol.2017.183202

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Figure 3. — Myelodysplastic syndromes (MDS) cells engraft in NSG-S mice. (A) Schematic representation of experimental set up. Patient-derived bone marrow mononuclear cells (MNC) alone or in combination with mesenchymal stem cells (MSC) were intrafemorally injected in NSG-S mice. Characteristic gating strategy for analyzing the (B) myeloid (CD33), lymphoid (CD19, CD3), progenitor (CD45RA, CD123, CD38) and (C) erythroid (GlyA) subpopulations found in the bone marrow of mice engrafted with patients’ bone marrow MNC samples. Immunostainings of (D) hCD33, (E) glycophorin C and (F) GPIIIa of decalcified bone marrow sections from sternums of mice engrafted with human MDS.