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. 2018 Mar 22;103(6):939–948. doi: 10.3324/haematol.2017.181354

Figure 5.

Figure 5.

JQ1 treatment accelerates blood recovery after myeloablation. Animals were injected daily with 50 mg/kg JQ1 intraperitoneal (i.p.) for 21 days before receiving sublethal whole body irradiation with 5 Gy. (A and B) Flowcytometric quantification of hematopoietic stem cells (HSC) (A) and MPP (B) over the course of six weeks after myelosuppression (n=3–5; *P<0.05). (C–H) Analysis of the recovery of leukocytes (C), B cells (D), T cells (E), monocytes (F), thrombocytes (G) and granulocytes (H) after myelosuppression over the course of six weeks (n=3–5; *P<0.05).