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. 2018 Mar 22;103(6):1047–1053. doi: 10.3324/haematol.2017.177139

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Figure 1. — Survival data according to number of focal lesions (FLs). Progression-free survival (PFS) (upper panel) and overall survival (OS) (lower panel) for patients entered into TT4-6 trials by the number of FL detected at presentation: (A) all patients, (B) GEP70 low-risk patients, and (C) GEP70 high-risk patients. A significant difference was observed for patients with FLs at baseline compared to patients with no FL at baseline for both PFS (P<0.0001) and OS (P<0.0001). These differences were significant when considering separately GEP70 low-risk patients (P=0.0007 for PFS, P<0.0001 for OS) and GEP70 high-risk patients (P=0.04 for PFS, P=0.05 for OS).