Figure 3.

Body weight of mice at different ages. (A) Overall body weight was lower in both KO and HET than in CTR mice. CTR mice were heavier than HET mice, and the latter were heavier than KO mice. Furthermore, male mice were heavier than female mice. Data originate from all mice used for behavioral experiments (n = 55 CTR, 31 HET, 36 KO). Nest assessment: KO mice build nests of lower quality than CTR and HET mice (B). Circles filled in light and dark gray represent data of single female and male mice, respectively. There was no sex difference in the quality of nests built overnight by the individually housed mice, however CTR mice built nests of higher quality than KO mice. Quality ratings were assessed by a blinded observer. (n = 12 CTR, 13 HET, 6 KO). (#p < 0.05, ###p < 0.001).