Table 4.
Discrimination performances (overall accuracy (Acc), sensitivity (Sen), and Specificity (Spe)) of each structure by combining the volume feature and each of the three shape features at different dimensions (original – no dimension reduction; PCA — dimension reduced via PCA; PCA + ttest — dimension reduced via PCA followed by a Student's t-test) with two classification algorithms — LDA and SVM.
| LDA | SVM | ||||||
|---|---|---|---|---|---|---|---|
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| Original | PCA | PCA + ttest | Original | PCA | PCA + ttest | ||
| Left Hippocampus | Acc | 56.8% | 78.4% | 75.7% | 83.8% | 83.8% | 75.7% |
| Sen | 40.9% | 72.7% | 68.2% | 77.3% | 86.4% | 68.2% | |
| Spe | 80.0% | 86.7% | 86.7% | 93.3% | 80.0% | 86.7% | |
| Right Hippocampus | Acc | 59.5% | 73.0% | 86.5% | 78.4% | 73.0% | 89.2% |
| Sen | 50.0% | 59.1% | 81.8% | 72.7% | 68.2% | 86.4% | |
| Spe | 73.3% | 93.3% | 93.3% | 86.7% | 80.0% | 93.3% | |
| Left Amygdala | Acc | 51.4% | 70.3% | / | 62.2% | 70.3% | / |
| Sen | 54.5% | 63.6% | / | 59.1% | 72.7% | / | |
| Spe | 46.7% | 80.0% | / | 66.7% | 66.7% | / | |
| Right Amygdala | Acc | 29.7% | 62.2% | / | 59.5% | 48.6% | / |
| Sen | 31.8% | 50.0% | / | 59.1% | 31.8% | / | |
| Spe | 26.7% | 80.0% | / | 60.0% | 73.3% | / | |
Note: Student's t-tests were not applicable for the amygdalar shape features.