Table 1.

Physiologic Characteristics of Two Groups of Rats Ventilated in the Prone versus Supine Position after Hydrochloric Acid Instillation in the Trachea

	Supine			Prone
	Baseline	1 h	2 h	Baseline	1 h	2 h*
Arterial blood pressure, mm Hg	113.8 ± 12.3	108.9 ± 19.9	82.9 ± 41.9†	126.0 ± 8.4	118.2 ± 23.1	104.8 ± 28.5†
Driving pressure, cm H2O	19.1 ± 2.9	23.3 ± 5.6†	28.7 ± 6.6†	19.9 ± 2.2	20.7 ± 3.3	21.8 ± 4.0‡
Po2, mm Hg	396.3 ± 79.7	107.5 ± 56.5†	43.6 ± 7.5†	388.8 ± 65.9	217.0 ± 109.3†‡	142.9 ± 108.1
Pco2, mm Hg	45.9 ± 8.2	50.0 ± 11.2	50.6 ± 10.2	46.4 ± 6.7	44.8 ± 7.8	48.7 ± 11.1
pH	7.34 ± 0.06	7.26 ± 0.06†	7.19 ± 0.04†	7.32 ± 0.07	7.29 ± 0.01	7.30 ± 0.06
SpO2, %	99.9 ± 0.1	94.5 ± 4.9†	65.9 ± 11.7†	99.9 ± 0.1	99.0 ± 0.8	94.4 ± 7.5†‡
Blood lactate, mmol/L	1.28 ± 0.40	2.50 ± 1.29†	4.82 ± 3.26†	1.54 ± 0.72	1.89 ± 1.38	1.49 ± 0.08

Definition of abbreviation: Sp_O2 = oxygen saturation as measured by pulse.

^*In the prone group, arterial blood gases were available at 2 hours in only three rats because of positional difficulties drawing blood through the carotid catheter after 1 hour of prone ventilation.

^†P < 0.05 versus baseline in the same group.

^‡P < 0.05 between cohorts.