Table 4.
Site-Specific Titin Phosphorylation
| Control | AS | cAS | pAS | ASrEF | p Value∗ | |
|---|---|---|---|---|---|---|
| P-S4010/PVDF (N2Bus) | 0.80 (0.76, 0.82) (n = 5) | 0.75 (0.65, 0.81) (n = 20) | 0.80 (0.69, 0.83) (n = 8) | 0.80 (0.68, 0.84) (n = 4) | 0.70 (0.65, 0.72) (n = 8) | 0.216 0.156 |
| P-S4099/PVDF (N2Bus) | 0.86 (0.83, 0.92) (n = 6) | 0.85 (0.78, 0.90) (n = 22) | 0.85 (0.78, 0.90) (n = 9) | 0.79 (0.76, 0.80) (n = 5) | 0.85 (0.78, 0.88) (n = 8) | 0.214 0.353 |
| P-S4185/PVDF (N2Bus) | 0.89 (0.88, 0.94) (n = 5) | 0.77 (0.70, 0.84) (n = 22) | 0.82 (0.74, 0.94) (n = 9) | 0.72 (0.69, 0.80) (n = 5) | 0.74 (0.61, 0.81) (n = 8) | 0.023 0.017 |
| P-S11878/PVDF (PEVK) | 0.91 (0.78, 1.00) (n = 6) | 0.94 (0.87, 0.98) (n = 21) | 0.94 (0.89, 0.98) (n = 9) | 0.97 (0.92, 1.02) (n = 4) | 0.88 (0.81, 0.98) (n = 8) | 0.712 0.570 |
Values are median (1st quartile, 3rd quartile).
∗
Upper p value compares control group and all AS subgroups using the Mann-Whitney U test. Lower p value compares control and subgroups of AS using the Kruskal-Wallis test.