Figure 3.

Allogeneic GFP^pos pPICs Stimulate Endogenous pPIC Activation

(A) Representative image of GFP^neg/PW1^pos/Pax7^neg pPICs resident in CTX-pPIC–treated skeletal muscle 14 days post-injury, scale bar = 50 μm. (B) Number of GFP^neg/PW1^pos/Pax7^neg pPICs per total nuclei, determined from 3 fields of view per muscle, n = 5 animals per group. Data are mean ± SD, *p = 0.0145 versus CTX-PBS–treated. (C) GFP^neg/PW1^pos/Pax7^pos satellite cells per total nuclei, determined from 3 fields of view per muscle, n = 5 animals per group. Data are mean ± SD. (D) Representative image of PW1^pos/Pax7^pos satellite cells resident in both CTX-PBS– and CTX-pPIC–treated skeletal muscle 14 days post-injury, scale bar = 50 μm. Abbreviations as in Figure 1.