Table 5.

Proposed domains and items for outcome measures of juvenile idiopathic arthritis (JIA)-associated uveitis (from the Multinational Working Group in JIA-related uveitis)⁷⁴

Domains	Items
Grade of cells in anterior chamber	Slit-lamp examination (according to SUN criteria)
Grade of flare in anterior chamber*	Slit-lamp examination for routine clinical practice and prospective trials (according to SUN criteria) Laser flare photometry for prospective trials
Number of visits with active uveitis	Records of treating physician Duration of activity over a minimum of four visits/year
Visual acuity (appropriate test for age)	Best-corrected visual acuity Thresholds: ≤20/50, ≤20/200 and no light perception Estimate contribution of amblyopia, yes/no
Development of structural complications	Synechiae, yes/no Initial and additional Ocular hypotony, yes/no (<5 mm Hg) Ocular hypertension, yes/no (>21 mm Hg) Glaucoma, yes/no Cataract, yes/no Band keratopathy in the central cornea, yes/no Macular oedema by optical coherence tomography, yes/no Funduscopy and optical coherence tomography for routine clinical practice (for macula and optic disc) Funduscopy and optical coherence tomography for prospective trials Epiretinal membrane formation, yes/no Funduscopy for routine clinical practice Funduscopy and optical coherence tomography for prospective trials
Quality of life	Childhood Health Assessment Questionnaire Child Health Questionnaire Pediatric Quality of Life Inventory Uveitis-specific quality of life instrument (not yet available for non-English speaking countries)
Overall uveitis-related disability	Assessment by parents, visual analogue scale Assessment by children, visual analogue scale Assessment by treating ophthalmologist, visual analogue scale Assessment by treating paediatric rheumatologist, visual analogue scale
Social outcome	School/kindergarten absence
Anti-inflammatory medication*	Reduction of corticosteroid dose—topical dose—systemic dose
Surgery*	Yes/no
Biomarkers	Research tools (not currently available

*Not an outcome measure, but should be documented.

SUN, Standardization of Uveitis Nomenclature.