Table 1.
Patient demographics and clinical characteristics
| ID | Age (years) | Sex | TBI mechanism | iGCS | Day of fMRI | CRS-R at fMRI | CRS-R subscale scores at fMRI | LoC at fMRI | Day of EEG | CRS-R at EEG | CRS-R subscale scores at EEG | LoC at EEG |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| P1 | 27 | M | MVA | 5 T | 16 | 23 | A4V5M6O3C2Ar3 | PTCS | 17 | 23 | A4V5M6O3C2Ar3 | PTCS |
| P2 | 21 | M | Ped versus car | 4–8 T | 1 | 4 | A0V0M3O1C0Ar0 | MCS− | 2 | 4 | A0V0M3O1C0Ar0 | MCS− |
| P3 | 19 | F | MVA | 5 T | 3 | 1 | A0V0M1O0C0Ar0 | Coma | 4 | 1 | A0V0M1O0C0Ar0 | Coma |
| P4 | 19 | M | Fall | 3–7 T | 17 | 23 | A4V5M6O3C2Ar3 | PTCS | 10 | 22 | A4V5M6O3C2Ar2 | PTCS |
| P5 | 34 | M | Fall | 5 T | 15 | 3 | A0V0M0O2C0Ar1 | VS | 16 | 3 | A0V0M0O2C0Ar1 | VS |
| P6 | 28 | F | MVA | 3 | 7 | 6 | A0V1M2O1C0Ar2 | VS | 10 | 11 | A3V2M3O1C0Ar2 | MCS+ |
| P7 | 45 | M | MVA | 5 T | 13 | 18 | A3V5M5O3C1Ar1 | MCS+ | 14 | 18 | A3V5M5O3C1Ar1 | MCS+ |
| P8 | 33 | M | Fall | 5–7 T | 8 | 20 | A4V5M5O2C2Ar2 | PTCS | 8 | 20 | A4V5M5O2C2Ar2 | PTCS |
| P9 | 32 | M | Ped versus car | 5–7 T | 11 | 9 | A3V2M2O1C0Ar1 | MCS+ | 13 | 15 | A3V3M5O1C1Ar2 | MCS+ |
| P10 | 24 | M | Assault | 3–7 T | 12 | 10 | A1V1M5O1C0Ar2 | MCS− | 13 | 10 | A1V1M5O1C0Ar2 | MCS− |
| P11 | 22 | F | Ped versus car | 6 T | 14 | 22 | A4V5M6O3C1Ar3 | PTCS | 14 | 22 | A4V5M6O3C1Ar3 | PTCS |
| P12 | 27 | F | Fall | 3 | 8 | 1 | A0V0M1O0C0Ar0 | Coma | 8 | 1 | A0V0M1O0C0Ar0 | Coma |
| P13 | 18 | M | Fall | 3–7 | 4 | 12 | A3V2M5O1C0Ar1 | MCS+ | 6 | 21 | A4V5M6O3C2Ar1 | PTCS |
| P14 | 51 | M | Ped versus car | 3 | 8 | 3 | A0V0M1O0C1Ar1 | VS | N/Aa | N/Aa | N/Aa | N/Aa |
| P15 | 29 | M | Ped versus car | 4–7 | 7 | 3 | A0V0M3O0C0Ar0 | MCS− | 8 | 7 | A3V0M3O0C0Ar1 | MCS+ |
| P16 | 33 | M | Fall | 3–4 | 3 | 12 | A4V2M5O0C0Ar1 | MCS+ | 4 | 14 | A4V2M6O0C0Ar2 | PTCS |
The initial Glasgow Coma Scale (iGCS) is defined as the best (i.e. highest) and worst (i.e. lowest) post-resuscitation GCS score assessed by a qualified clinician who performed a reliable examination (not confounded by sedation and/or paralytics) prior to ICU admission. Level of consciousness (LoC) is assessed via behavioural evaluation with the CRS-R as coma, vegetative state (VS), MCS−, MCS+, or PTCS (emerged from MCS but disoriented). The subscales for the CRS-R are Auditory Function (A), Visual Function (V), Motor Function (M), Oromotor Function (O), Communication (C), and Arousal (Ar).
F = female; fMRI = functional MRI; M = male; MVA = motor vehicle accident; N/A = not applicable; Ped = pedestrian.
aPatient died before EEG due to withholding of life-sustaining treatment.