Table 6.
Demographic | Standard biopsy, No. | Targeted biopsy, No. | NNB by target vs standard biopsy to diagnose one fewer Gleason 6 cancer |
---|---|---|---|
All men | 4.9 | 6.8 | 17.0 |
MRI suspicion | |||
Low | 3.7 | 5.2 | 12.6 |
Moderate | 4.9 | 6.7 | 18.0 |
High | 9.9 | 18.2 | 21.8 |
PSA quartiles, ng/mL | |||
<4.4 | 3.7 | 4.4 | 25.1 |
4.4–6.6 | 4.6 | 5.8 | 22.6 |
6.6–10.7 | 5.5 | 8.4 | 15.8 |
≥10.7 | 6.4 | 14.8 | 11.4 |
Prostate volume quartiles, cc | |||
<38 | 4.4 | 6.3 | 14.9 |
38–51 | 4.2 | 6.0 | 14.7 |
51–72 | 6.0 | 6.8 | 49.0 |
≥72 | 5.2 | 8.8 | 12.8 |
Age quartiles, y | |||
<57 | 4.7 | 6.3 | 18.8 |
57–62 | 4.2 | 5.8 | 15.3 |
62–67 | 5.0 | 6.1 | 28.6 |
≥67 | 5.6 | 10.0 | 12.6 |
Prior negative biopsy | |||
Yes | 7.3 | 12.6 | 17.2 |
No | 3.9 | 5.1 | 16.9 |
*MRI = magnetic resonance imaging; NNB = number of men who need to be biopsied; PSA = prostate-specific antigen.