Table 4.
Ganodermasp. | Extraction Solvent | Parts/compounds | Test Parasite | Method | LD50/IC50 value | References |
---|---|---|---|---|---|---|
Ganodermasp. | EtOAc&MeOH | Fruiting bodies(schisanlactone B(32), Ganodermalactone F(24), colossolactone E(6)) | P. falciparum | Micro culture Radioisotope Technique | 6.0–10.0 μM | (Lakornwong et al. 2014) |
G. lucidum | EtOAc&MeOH | Fruiting bodies* | P. falciparum | Micro culture Radioisotope Technique | 6.0-20μM | (Adams et al. 2010) |
G. boninense | EtOH | Ganoboninketals A(75) Ganoboninketals B-C(16–17) | P. falciparum | DNA Fluorescence Signal Test |
4.0, 7.9, and 1.7 μM | (Ma et al. 2014) |
G. lucidum | EtOH | Crude extract | P. berghei | In Vivo Malarial activity | (Oluba et al. 2012) | |
G.lucidum | NG | Lectin | H. glycines | Parasite Mortality Test | (>10 mg/ml/2hrs,4.5 mg/ml/24hrs, 1.7 mg/ml/48hrs | (Zhao et al. 2009) |
G. lucidum | NG | Lectin | D. dipsaci | Parasite Mortality Test | >10 mg/ml | (Zhao et al. 2009) |
EtoAc: Ethyl Acetate; EtOH: ethanol; MeOH: Methanol; P. falciparum: Plasmodium falciparum; H. glycines: Heteroderaglycines; D. dipsaci: Ditylenchusdipsaci; NG: Data Not Given; μM: Micro Mole; mg/ml: milligram/millilitre; *(Ganodericacid DM(35), Ganoderic Acid TR 1(52),Ganoderic Aldehyde TR(37),23-Hydroxyganoderic Acid S(36), Ganoderic acid S(18), Ganodermanondiol(37), Ganofuran B(49)).