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. 2017 May 24;8(2):111–124. doi: 10.1080/21501203.2017.1324529

Table 4.

Details of anti-parasitic activities of Ganoderma sp. parts and compounds.

Ganodermasp. Extraction Solvent Parts/compounds Test Parasite Method LD50/IC50 value References
Ganodermasp. EtOAc&MeOH Fruiting bodies(schisanlactone B(32), Ganodermalactone F(24), colossolactone E(6)) P. falciparum Micro culture Radioisotope Technique 6.0–10.0 μM (Lakornwong et al. 2014)
G. lucidum EtOAc&MeOH Fruiting bodies* P. falciparum Micro culture Radioisotope Technique 6.0-20μM (Adams et al. 2010)
G. boninense EtOH Ganoboninketals A(75) Ganoboninketals B-C(16–17) P. falciparum DNA Fluorescence
Signal Test
4.0, 7.9, and 1.7 μM (Ma et al. 2014)
G. lucidum EtOH Crude extract P. berghei In Vivo Malarial activity   (Oluba et al. 2012)
G.lucidum NG Lectin H. glycines Parasite Mortality Test (>10 mg/ml/2hrs,4.5 mg/ml/24hrs, 1.7 mg/ml/48hrs (Zhao et al. 2009)
G. lucidum NG Lectin D. dipsaci Parasite Mortality Test >10 mg/ml (Zhao et al. 2009)

EtoAc: Ethyl Acetate; EtOH: ethanol; MeOH: Methanol; P. falciparum: Plasmodium falciparum; H. glycines: Heteroderaglycines; D. dipsaci: Ditylenchusdipsaci; NG: Data Not Given; μM: Micro Mole; mg/ml: milligram/millilitre; *(Ganodericacid DM(35), Ganoderic Acid TR 1(52),Ganoderic Aldehyde TR(37),23-Hydroxyganoderic Acid S(36), Ganoderic acid S(18), Ganodermanondiol(37), Ganofuran B(49)).