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. 2017 Aug 1;110(2):176–182. doi: 10.1093/jnci/djx135

Table 2.

Odds ratios for breast cancer subtype by patient characteristics

PAM50 subtype Age, y
Race
≥50 <50 OR* (95% CI) OR (95% CI) P White, Black, OR§ (95% CI) OR (95% CI) P
No. (%) No. (%) No. (%) No. (%)
LumA 217 (44.6) 160 (35.8) 1.00 (reference) 1.00 (reference) .06 228 (50.2) 149 (31.0) 1.00 (reference) 1.00 (reference) <.001
Basal-like 120 (24.6) 129 (28.7) 1.54 (1.10 to 2.14) 1.08 (0.72 to 1.62) 80 (17.6) 169 (35.2) 3.11 (2.22 to 4.37) 1.93 (1.27 to 2.93)
LumB 94 (19.3) 100 (22.4) 1.47 (1.04 to 2.09) 1.21 (0.83 to 1.77) 98 (21.6) 96 (20.0) 1.45 (1.02 to 2.06) 1.14 (0.78 to 1.68)
HER2-enriched 56 (11.5) 58 (13.0) 1.45 (0.95 to 2.22) 1.12 (0.70 to 1.79) 48 (10.6) 66 (13.8) 2.04 (1.33 to 3.13) 1.43 (0.88 to 2.30)
Normal-like 25 21 26 20
*

Adjusted for race. CI = confidence interval; HER2 = human epidermal growth factor receptor 2; OR = odds ratio.

Additionally adjusted for tumor size (≤2 cm vs > 2 cm), nodal status (negative vs positive), stage (I and II vs III and IV), and grade (I and II vs III).

Two-sided chi-square P values exclude 46 cases with normal-like PAM50 subtype and 138 cases with unclassified/missing clinical subtype.

§

Adjusted for age.