Table 2.

Effect of LAC on cytokines secretion in non-specific immune response.

Group	Dose (mg/kg)	Con A (5 μg/mL)	LPS (10 μg/mL)
		IL-2 (pg/mL)
NC	–	221.44 ± 56.47	53.37 ± 9.86
LAC	198	293.43 ± 67.66*	86.92 ± 17.35*
LAC	593	291.99 ± 61.01*	85.73 ± 15.81*
LAC	988	307.87 ± 45.74*	86.35 ± 23.85*
PC	260	262.87 ± 51.48	69.70 ± 21.97
		IL-4 (pg/mL)
NC	–	21.25 ± 9.80	4.92 ± 1.34
LAC	198	21.28 ± 7.19	7.28 ± 3.36
LAC	593	19.10 ± 5.90	7.25 ± 3.70
LAC	988	17.72 ± 4.30	7.53 ± 2.89
PC	260	14.86 ± 7.50	5.09 ± 1.80
		TNF-α (pg/mL)
NC	–	313.93 ± 107.64	221.79 ± 90.35
LAC	198	410.36 ± 82.17*	331.79 ± 125.30
LAC	593	410.24 ± 106.57*	433.81 ± 176.07*
LAC	988	417.19 ± 77.95*	410.00 ± 138.37*
PC	260	442.19 ± 90.03*	293.08 ± 77.07
		IFN-γ (pg/mL)
NC	–	1329.82 ± 345.51	186.23 ± 58.04
LAC	198	1698.73 ± 323.08*	204.77 ± 67.81
LAC	593	1690.90 ± 360.44*	276.86 ± 97.37*
LAC	988	1765.42 ± 207.41*	270.92 ± 109.60*
PC	260	1737.08 ± 210.89*	199.36 ± 76.81
		GM-CSF (pg/mL)
NC	–	226.52 ± 62.19	21.04 ± 4.13
LAC	198	290.70 ± 42.21*	25.33 ± 6.32
LAC	593	317.65 ± 95.27*	31.47 ± 7.95*
LAC	988	316.36 ± 68.19*	29.57 ± 9.55*
PC	260	214.17 ± 70.38	21.96 ± 7.85

All data were presented as mean ± SD.

NC: normal control; PC: positive control.

LAC: solid-state cultivated powder of T. camphoratus.

*p < 0.05 compared to normal control.