Table 3.

Effect of LAC on cytokines secretion in specific immune response.

Group	Dose (mg/kg)	Con A (5 μg/ml)	OVA (50μg/ml)
		IL-2 (pg/ml)
NC	–	125.4 ± 41.6	9.5 ± 3.8
LAC	198	241.3 ± 81.5*	14.4 ± 3.9*
LAC	593	234.9 ± 85.8*	15.1 ± 3.7*
LAC	988	239.7 ± 66.3*	15.7 ± 5.5*
PC	260	144.9 ± 57.4	10.2 ± 4.2
		IL-4 (pg/ml)
NC	–	17.1 ± 4.5	11.5 ± 3.1
LAC	198	18.9 ± 7.2	12.0 ± 2.5
LAC	593	16.0 ± 6.9	11.2 ± 4.8
LAC	988	16.1 ± 5.9	11.0 ± 3.9
PC	260	14.4 ± 5.1	11.0 ± 4.5
		TNF-α (pg/ml)
NC	–	145.5 ± 27.7	26.3 ± 8.2
LAC	198	462.5 ± 151.8*	37.5 ± 4.3
LAC	593	449.2 ± 163.4*	35.0 ± 20.4
LAC	988	456.8 ± 183.8*	31.9 ± 12.9
PC	260	196.7 ± 75.1	20.7 ± 7.9
		IFN-γ (pg/ml)
NC	–	688.2 ± 140.3	22.1 ± 7.0
LAC	198	1124.4 ± 529.8*	34.0 ± 7.4*
LAC	593	1118.2 ± 534.2*	36.2 ± 7.9*
LAC	988	1287.4 ± 583.6*	33.3 ± 7.8*
PC	260	709.2 ± 219.2	20.9 ± 4.8
		GM-CSF (pg/ml)
NC	–	52.8 ± 13.3	3.2 ± 3.5
LAC	198	81.9 ± 15.5*	2.3 ± 2.3
LAC	593	81.1 ± 17.8*	3.2 ± 3.0
LAC	988	81.5 ± 20.7*	3.5 ± 2.6
PC	260	60.3 ± 13.2	4.4 ± 2.6

All data were presented as mean ± SD.

NC: normal control; PC: positive control.

LAC: solid-state cultivated powder of T. camphoratus.

*p < 0.05 compared to normal control.