Figure 4.

Stress suppresses multiplexed task-related spiking activity. (a) Multiplexed responses of delay-tuned neurons. (ai) Spiking rasters and PETHs of a delay-tuned neuron also responsive to pickup (PETH aligned to pickup). (aii) Overall, stress suppressed pickup-related spiking activity of delay-tuned neurons suggesting that PFC neuron error signals carried by delay neurons are suppressed by stress (n = 17). Multiplexed reward (aiii, n = 18) and choice-related (aiv, n = 21) responses of delay-tuned neurons were also suppressed by stress. (b) Choice-related responses of reward-tuned multiplexing neurons are suppressed during stress (n = 27). *P < 0.05; **P < 0.01.