Figure 1.

Results from whole-brain vertex-wise analysis of cortical metrics between children with dyslexia compared with typically decoding peers, controlling for age (vertex-wise threshold of P < 0.01) for (A) cortical thickness and (C) LGI (C). Statistical maps are depicted on the inflated surface to allow visualization of sulci (dark gray) as well as gyri (light gray). Regions that remained significant following a cluster-based multiple comparison correction procedure are outlined in green (cluster-wise threshold, P < 0.05). (B) Spatial overlap (purple) of regions demonstrating reduced cortical thickness (blue) and increased LGI (red) among children with dyslexia compared with typically decoding peers, controlling for age. All labeled clusters were significant based on a voxel-wise threshold of P < 0.01 and remained significant following multiple comparison correction using a cluster-wise threshold of *P < 0.05 (corresponding to clusters outlined in green in A and C).