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. 2018 Jul 3;5(1):e000812. doi: 10.1136/openhrt-2018-000812

Table 1.

Characteristics of included studies

Author/study Year Country Design Sample size Age
(SD)		 Male (%) Fontan procedure, n (%) Follow-up Late outcome NOS
Diller et al 22 2010 UK, Germany and
Italy		 Retrospective cohort study 321 21±9 56 APC/AVC: 150 (46.7).
EC/LT: 171 (53.3).		 21 months

  1. All-cause mortality and transplantation.

  2. Cardiac-related hospitalisation.

 8/9
Fernandes et al 23 2011 USA Retrospective cohort study 146 21.5 (range 16.0–51.6) 54 * 4 years

  1. All-cause mortality.

  2. Combined endpoint (mortality or a new morbidity).

 7/9
Ohuchi et al 24 2015 Japan Retrospective cohort study 335 18±9 64 APC: 19 (5.7).
LT: 94 (28).
EC: 222 (66.3).		 3.1 years

  1. All-cause mortality.

  2. Unscheduled hospitalisation.

 8/9
Nathan et al 26 2015 USA Retrospective cohort study 253
(95)		 19±9 58 APC: 27%.
LT: 67%.
EC: 5%.
AVC: 1%.		 5.5 years

  1. All-cause mortality and transplantation.

  2. Death, Fontan-related events or hospitalisation.

 8/9
Egbe et al 25 2017 USA Retrospective cohort study 145
(71)		 24±3 63 APC: 107 (74).
LT: 29 (20).
EC: 9 (6).		 8 years

  1. Cardiovascular adverse events (death and cardiac surgery).

 7/9
Atz et al 27 2017 USA Retrospective cohort study 334 21±4 † † 9.4 years

  1. All-cause mortality and transplantation.

 8/9
Cunningham et al 28 2017 USA Retrospective cohort study 130 26.6±9.5 58 APC: 32 (25).
LT: 79 (61).
EC: 15 (12).
AVC: 4 (3).		 1.4 years

  1. All-cause mortality and transplantation.

  2. Death, transplantation, Fontan-related events or hospitalisation.

 8/9

*Not reported for the entire cohort.

†Reported in an earlier cross-section.

AVC, atrioventricular connection; APC, atriopulmonary connection; EC, extracardiac; LT, lateral tunnel; NOS, Newcastle-Ottowa Scale.