Table 3.

Summary of number and type of single-item and multiitem measurement tools used

Single-item scales:
Pain on activity:	WOMAC Q1 3.0 VAS ‘pain on walking on a flat surface’ (0–100 mm) (n=11) Pain on walking VAS (0–100 mm) (n=5) Pain on movement VAS (0–100 mm); ambulatory pain (5-point Likert); pain with physical activity VAS 11-point scale (n=2)
Pain (not further specified):	Pain VAS (0–100 mm) (n=15) Patients assessment of pain score (0–10); pain scale (0–3); Pain NRS (0–10) (n=11)
Standing knee pain	Item 5 WOMAC pain scale (n=1)
Global rating (physician/investigator)	Investigator Assessment of Disease Status (n=11) Physicians Global Assessment of Arthritis (n=6) Physician Global Assessment of OA (n=2) Physician Global Assessment of Disease Status (n=2); Investigator Assessed Pain Grade; (Physician) Overall Disease Activity (0–100); Physicians Pain Assessment (4-point LK) (n=3)
Global rating (patient)	Patients Global Assessment of Arthritis (n=7) Patient Global Assessment of OA (n=3) Patient Global Assessment of Disease Status (n=4)
Multiple-item scales:
	Lequesne OA Severity Index (n=5) WOMAC LK3.1 (0–20) (n=3) WOMAC LK Pain subscale (0–25); WOMAC OA Index Questionnaire (n=1); WOMAC knee pain score (0–500) [n=7]; KOFUS (0–14) (n=1)

KOFUS, Knee Osteoarthritis Flare-up Score; LK, Likert scale; N, number of included studies; OA, osteoarthritis; VAS, Visual Analogue Scale; WOMAC, Western Ontario and McMaster Universities Osteoarthritis Index.