Table 2. Characteristics of elderly patients diagnosed with dementia and their unadjusted associations with mortality in the derivation group determined by using Cox proportional hazards regression with time-dependent covariates.

	Univariate analysis		Multivariate analysis
Characteristics	Crude HR (95% CI)	P value	Adjusted HR (95% CI)	P value
Age, years
65–69	1.00		1.00
70–74	1.29 (1.19–1.39)	<0.0001	1.13 (1.05–1.22)	0.0011
75–79	1.62 (1.51–1.74)	<0.0001	1.34 (1.24–1.43)	<0.0001
80–84	2.12 (1.98–2.28)	<0.0001	1.72 (1.60–1.84)	<0.0001
85+	3.12 (2.90–3.35)	<0.0001	2.45 (2.28–2.64)	<0.0001
Sex
Female	1.00		1.00
Male	1.41 (1.36–1.45)	<0.0001	1.20 (1.16–1.25)	<0.0001
Comorbidity
Hypertension	1.14 (1.09–1.19)	<0.0001	0.93 (0.89–0.97)	0.0018
CAD	1.12 (1.08–1.16)	<0.0001	0.92 (0.89–0.96)	<0.0001
CHF	1.46 (1.41–1.52)	<0.0001	1.10 (1.05–1.14)	<0.0001
Hyperlipidemia	0.82 (0.79–0.85)	<0.0001	0.92 (0.89–0.96)	<0.0001
Diabetes	1.17 (1.14–1.22)	<0.0001	1.14 (1.09–1.18)	<0.0001
Cancer	1.75 (1.65–1.85)	<0.0001	1.71 (1.61–1.81)	<0.0001
Stroke	1.69 (1.63–1.74)	<0.0001	1.37 (1.32–1.42)	<0.0001
Chronic Renal failure	1.77 (1.69–1.85)	<0.0001	1.43 (1.36–1.50)	<0.0001
COPD	1.77 (1.69–1.85)	<0.0001	1.06 (1.02–1.10)	0.0015
Liver cirrhosis	1.68 (1.51–1.86)	<0.0001	1.33 (1.20–1.48)	<0.0001
Pressure injury	2.02 (1.91–2.13)	<0.0001	1.42 (1.34–1.50)	<0.0001
Hospitalization
Ward care ≥ 2 times	2.83 (2.74–2.93)	<0.0001	1.20 (1.15–1.25)	<0.0001
Emergency services ≥ 1 times	2.54 (2.45–2.63)	<0.0001	1.24 (1.20–1.29)	<0.0001
Medical procedure
NG tube placement	3.72 (3.58–3.87)	<0.0001	1.52 (1.44–1.60)	<0.0001
Oxygen supply	3.61 (3.48–3.75)	<0.0001	1.54 (1.46–1.61)	<0.0001
ET ≥ 2 times	3.96 (3.83–4.10)	<0.0001	1.88 (1.80–1.96)	<0.0001
CPR ≥ 2 times	3.27 (3.15–3.39)	<0.0001	1.51 (1.45–1.58)	<0.0001

CAD, Coronary artery disease; CHF, chronic heart failure; COPD, chronic obstructive pulmonary disease; NG, nasogastric; ET, endotracheal intubation; CPR, cardiopulmonary resuscitation.