Table 3. Distribution of genotypic frequencies with respect to the GATA3 gene in Type 2 diabetic patients and healthy individuals.
| Parameters | Type 2 diabetic patients n (%) | Healthy Controls n (%) | OR, (95% CI Lowest-Highest) | χ2 | p | |
|---|---|---|---|---|---|---|
| Genotype | GG/GT/TT | 154/116/27 | 153/85/9 | - | - | - |
| Alleles | G/T | 424/170 (71.38/28.62) |
391/103 (79.15/20.85) |
1.52 (1.15–2.02) | 8.66 | <0.01 |
| Co-dominant model | GG | 154 (51.85) | 153 (61.94) | 1 | - | - |
| GT | 116 (39.06) | 85 (34.41) | 2.98 (1.36–6.55) | 7.98 | <0.01 | |
| TT | 27 (9.09) | 9 (3.64) | 1.36 (0.95–1.94) | 2.78 | 0.095 | |
| Dominant model | GG | 154 | 153 | 1 | - | - |
| GT+TT | 143 (48.14) | 94 (38.06) | 1.51 (1.07–2.13) | 5.33 | 0.018 | |
| Recessive | GG+GT | 270 (90.90) | 238 | 1 | - | - |
| TT | 27 | 9 | 0.37 (0.17–0.82) | 6.47 | 0.011 | |
| Over dominant | GG+TT | 181 (60.94%) | 162 (65.59) | 1 | - | - |
| GT | 116 | 85 | 0.82 (0.57–1.16) | 1.25 | 0.263 | |
OR: Odds ratio; CI: Confidence interval; χ2: Chi square