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. 2018 Jul 25;13(7):e0201199. doi: 10.1371/journal.pone.0201199

Table 1. Clinical characteristics of patients in the PAF and non-PAF groups.

Variables Total PAF non-PAF P Value
Patients, n (%) 118 73 (61.8) 45 (38.1)
Male sex, n (%) 102(86.4) 61 (83.5) 41 (91.1) 0.28
Age, years (IQR) 58 (50–62) 59 (49.5–62) 58 (51–62) 0.98
BMI, kg/m2 (IQR) 23.8 (21.6–26.5) 23.8 (21.7–26.7) 23.9(21.3–26.1) 0.88
Duration of AF, months (IQR) 26 (7–72) 36(6.5–72) 24 (7–14) 0.46
Hypertension, n (%) 37 (31.3) 23 (31.5) 14 (31.1) 1
Diabetes mellitus, n (%) 11(9.3) 7(9.6) 4(8.9) 1
Stroke, n (%) 10(8.5) 5(6.8) 5(11.1) 0.50
History of TCM, n (%) 9(7.6) 5(6.8) 4(8.9) 0.73
Pre-ablation anti-arrhythmic drugs
    Class Ⅰ AAD, n (%) 46(39.0) 37(50.7) 9(20.0) <0.001*
    Class Ⅲ AAD, n (%) 2(1.7) 1(1.4) 1(2.2) 1
    βblocker, n (%) 50(42.4) 27(37.0) 23(51.1) 0.18
    ACEI/ARB, n (%) 34(28.8) 18(24.7) 16(35.6) 0.22
Statin, n (%) 25(21.2) 12(16.4) 13(28.9) 0.16
LV ejection fraction, % (IQR) 67(61.8–71.0) 69(65–72) 64(59–68) <0.0001*
Left atrial anteroposterior echocardiographic dimension, mm (IQR) 41(37–44) 40(36–43) 42(39–46) 0.008*
NT proBNP, pg/ml (IQR) 118(51–382) 67(30–135) 391(223–818) <0.0001*
Recurrent patients, n (%) 42(35.6) 23(31.5) 19(42.2) 0.23
Recurrence time, months (IQR) 6.5(3.2–9.7) 7.0(4.0–10.5) 6.0(3.0–9.0) 0.75

Data are n (%), and median (IQR; 25%―75% interquartile range).

* significant difference

AAD, anti-arrhythmic drug; ACEI, angiotensin converting enzyme inhibitor; ARB, angiotensin II receptor blocker; BMI, body mass index; LV, left ventricle; non-PAF, non-paroxysmal atrial fibrillation; PAF, paroxysmal atrial fibrillation; TCM, tachycardia-induced cardiomyopathy