Table 1.
Selected characteristics of PKAN study subjects including disease severity scales, diet survey results and body habitus. Body habitus of matched controls are also reported here.
| PKAN participants | Control participants | |||||||
|---|---|---|---|---|---|---|---|---|
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|
|
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| All (n = 16) | Ages 19+ (n = 10) | Ages 18 & under (n = 6) | Females (n = 10) | Males (n = 6) | All (n = 16) | Females (n = 10) | Males (n = 6) | |
| Body habitus: | ||||||||
| Age (y) | 25 ± 15 | 31 ± 15 | 14 ± 4 | 25 ± 18 | 24 ± 10 | 25 ± 15 | 25.6 ± 18.0 | 24.0 ± 8.8 |
| Weight (kg) | 57.9 ± 18.5 | 64 ± 17 | 49 ± 18 | 52 ± 19 | 67 ± 15 | 58.1 ± 13.5 | 53.8 ± 11.8 | 64.3 ± 13.5 |
| Height (cm) | 162 ± 16.1 | 167 ± 12 | 153 ± 20 | 157 ± 14 | 170 ± 18 | 164.5 ± 15.1 | 159.0 ± 14.0 | 173.1 ± 12.8 |
| BMI (kg/m2) | 22 ± 5 | 23 ± 5 | 20 ± 4 | 21 ± 6 | 23 ± 2 | 21.1 ± 2.6 | 20.9 ± 2.5 | 21.4 ± 2.7 |
| Body fat (% weight) | 21.4 ± 10.0 | 22 ± 11 | 21 ± 9 | 23 ± 11 | 19 ± 8 | Not given | ||
| Severity scales: | ||||||||
| Global | 3.4 ± 1.5 | 3.3 ± 1.5 | 3.5 ± 1.5 | 3.6 ± 1.5 | 3.0 ± 1.4 | NA | ||
| BAD | 19 ± 7 | 17 ± 6.6 | 21 ± 7.5 | 21 ± 6.7 | 15 ± 6.4 | |||
| UPDRS | 42 ± 17 | 39 ± 17 | 45 ± 18 | 44 ± 20 | 38 ± 11 | |||
| CCHQ | 2.5 ± 1.1 | 2.1 ± 0.7 | 3.0 ± 1.4 | 2.9 ± 1.1 | 1.8 ± 0.4 | |||
| Electroretinogram scale | 2.3 ± 1.2 | 2.0 ± 1.1 | 2.8 ± 1.3 | 2.4 ± 1.3 | 2.2 ± 1.2 | |||
| Diet: | ||||||||
| Diet Habit Survey Score | 160 ± 20 | 164 ± 23 | 153 ± 13 | 158 ± 21 | 163 ± 20 | |||
| Estimated kcal/day | 2150 ± 510 | 2360 ± 340 | 1820 ± 600 | 1990 ± 540 | 2430 ± 340 | 1800a | 2200a | |
| Estimated % fat in diet | 30% | 30% | 30% | 30% | 30% | |||
Footnotes: y = years; kg = kilograms; cm = centimeters; BMI = body mass index; m = meters; body fat expressed as a percent (%) of total body weight; RQ = quotient calculated as VCO2/VO2.
a
Predicted intake for normal health.