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. 2018 May 4;18(1):131–138. doi: 10.3892/mmr.2018.8976

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Copyright: © Shi et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — Effect of treatment with Aidi on angiogenesis and VM in HUVECs and esophageal squamous cell carcinoma cells. (A) The anti-angiogenesis effect of treatment with Aidi on HUVECs, and the anti-VM formation effect of treatment with Aidi on KYSE70 cells after 24 h. Magnification, ×100. (B) Treatment with Aidi reduced the VEGF protein expression in EC9706 and KYSE70 cells. All values are presented as the mean ± standard deviation. **P<0.01 vs. respective contro1. VM, vasculogenic mimicry; HUVECs, human umbilical vein endothelial cells; VEGF-A, vascular endothelial growth factor A; AD, Aidi; 5-Fu, 5-fluorouracil.