Table I.

Ran, Ki-67 expression and clinicopathological parameters in 140 breast cancer specimens.

		Ran expression
	Total	Low	High	P-valuea	χ2
Age (years)
≤50	57	16	41	0.161	1.959
>50	83	15	68
Grade
I	17	13	4	0.000b	38.269
II	60	14	46
III	63	4	59
ER
Negative	69	14	55	0.602	0.270
Positive	71	17	54
PR
Negative	70	14	56	0.541	0.372
Positive	70	17	53
ErBb2
Negative	68	15	53	0.981	0.001
Positive	72	16	56
Size
≤2×2×2	77	19	58	0.424	0.636
>2×2×2	63	12	51
Axillary lymph node status
N0	52	15	37	0.141	2.156
Nx	88	16	72
Nerve invasion and metastasis
Negative	85	25	60	0.010b	6.631
Positive	55	6	49
Vascular metastasis
Negative	75	23	52	0.009b	6.807
Positive	65	8	57
Histology
Ductal	109	26	83	0.360	0.835
Others	31	5	26
Ki-67
Low	52	22	30	0.000b	19.512
High	88	9	79

^aStatistical analyses were performed by the Pearson χ2 test

^bP<0.05 was considered as statistically significant.