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. 2018 May 16;18(1):715–722. doi: 10.3892/mmr.2018.9022

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Copyright: © Zhang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — Effect of PYGB siRNA on the expression of E-cadherin, Twist, MMP9, MMP2, Bax and Bcl2 in the osteosarcoma cell lines MG63 and HOS. (A) The blots show the results of western blot analysis. The protein expression levels in (B) MG63 and (C) HOS cells were measured by western blot analysis 48 h following treatment with PYGB siRNA. *P<0.05, **P<0.01 and ***P<0.001 vs. the NC group. Data are expressed as the mean ± standard deviation (n=3). PYGB, Brain type glycogen phosphorylase; NC, negative control; siRNA, small interfering RNA; MMP, matrix metalloproteinase; Bcl2, B-cell lymphoma 2; Bax, Bcl-2-associated X protein.