Table I.
Cell line | IC50 (µg/ml) |
---|---|
A375 | 9.462±1.78 |
Colo201 | 13.02±0.34 |
SW620 | 32.87±0.76 |
MCF-7 | 16.89±1.40 |
MCF-10A-2 | 67.89±2.64 |
Hs68 | 40.46±1.39 |
Cells were treated with various concentrations of the steroid for 72 h; and cell viability was determined by the MTT assay. The IC50 concentrations represented the concentration of the steroid, which resulted in 50% inhibition of cell viability in relation to control after incubation. Results are expressed as mean value of three independent experiments. The IC50 values were obtained from linear regression of analysis (r2>0.97). 9(11)-DHEP, 9,11-dehydroergosterol peroxide.