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(A, B, E and F) High expression of RRM2 is associated with less favorable outcome in melanoma patients. Patients with melanoma were analyzed by Kaplan-Meier survival estimation (log-rank test). (C, D, G and H) Representative plots of patients with differential expression of RRM2: normalized (C and G) and z-score (D and H). OS, overall survival; DFS, disease-free survival; RRM2, ribonucleotide reductase family member 2.
