Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 May 16;40(1):165–178. doi: 10.3892/or.2018.6438

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Xin et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

Figure 9. — SOG production in SGC-7901 cells treated with AlPcS₄ + 5-FU, AlPcS₄ + CDDP, AlPcS₄ + DOX, AlPcS₄ + MMC, AlPcS₄ + VCR and free-AlPcS₄. (A-E) Fluorescence intensities of SOSGR probes were measured to analyze SOG in SGC-7901 cells after treatment with 1–32 µm free-AlPcS₄. (A) AlPcS₄ + 5-FU (20 µm), (B) AlPcS₄ + DOX (0.4 µm/ml), (C) AlPcS₄ + MMC (0.5 µm/ml), (D) AlPcS₄ + CDDP (5 µm) or (E) AlPcS₄ + VCR (0.1 µm/ml) and irradiation with 635-nm laser light for 5 min. Data represent the average of three experiments and the bar is the SD. *P<0.05 and **P<0.01 represent a statistically significant difference in the fluorescence intensity of SOSGR in cells between the combination therapy of AlPcS₄ with a chemical agent and single therapy of free-AlPcS₄. AlPcS₄, Al(III) phthalocyanine chloride tetrasulfonic acid; 5-FU, 5-fluorouracil; DOX, doxorubicin; CDDP, cisplatin; MMC, mitomycin C; VCR, vincristine; SOG, singlet oxygen.