Effect of ApoA-I Infusions on Late-Stage Aortic Sinus Atheroma
Aortic sinus sections were quantified histologically for plaque area (A), F4-80+ macrophage content (B), extracellular lipid content (C), and α-actin+ SMC content (D). Upper panels of A, B, and D display images of representative sections (scale bar indicates 200 μm). Data are mean ± SD. Baseline n = 5, saline n= 18, apoA-I n = 17 mice/treatment. *p ≤ 0.05. ApoA-I = apolipoprotein A-I; NS = not significant; SMC = smooth muscle cell.