Fig. 1.
Quantifying allelic bias of expression in human individuals using the RNA-seq read count ratio statistic Sig. The strength of bias towards the expression of the maternal (red) or paternal (blue) allele of a given gene g in individual i is gauged with the count of RNA-seq reads carrying the reference allele (small closed circles), and the count of reads carrying an alternative allele (open squares) at all SNPs for which the individual is heterozygous. The allele with the higher read count tends to match the allele with the higher expression, but measurement errors may occasionally revert this tendency as seen for SNP s3 in gene g1 in individual i2