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. 2018 Jul 25;8:11195. doi: 10.1038/s41598-018-29581-6

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Micronucleus frequency per mill (%_o) among the subgroups of obese subjects before surgery. (A) Comparison of micronucleus frequency between all patients, nondiabetic (ND), IR/T2DM, nonhypertensive (NH), hypertensive (H), nonmetabolic syndrome (NMetS) and metabolic syndrome (MetS). (B) Comparison of micronucleus frequency between IR/T2DM, hypertensive (H) and metabolic syndrome (MetS) before and after surgery. (C) Comparison of micronucleus frequency between a subgroup of HbA1c < 6 and HbA1c ≥ 6 before and after surgery. Before surgery, n_All = 45, n_ND = 19, n_IR/T2DM = 26, n_NH = 16, n_H = 29, n_NMetS = 31 and n_MetS = 14; 6 M, n_IR/T2DM = 21, n_H = 21, and n_MetS = 10; 12 M, n_IR/T2DM = 26, n_H = 29 and n_MetS = 14. *p ≤ 0.05 significant vs. All or vs. Before_IR/T2DM or vs. Before_MetS, ^#p ≤ 0.05 significant vs. ND or vs. Before_HbA1c≥6 and op ≤ 0.05 significant vs. NMetS.