Table 1.
List of antibiotic resistance genes (ABR) and mobile elements on the custom designed ABR microarray according to class/type.
| Antibiotic Classes/Types | Total Genes |
|---|---|
| Aminoglycoside | |
| aac(3)-Ia, aac(3)-Id, aac(3)-IIa, aac(3)-IIIa, aac(3)-Iva, aac(3)-Via, aac(6′)-aph(2″), aac(6′)-Ib-cr, aac(6′)-Im, aac6-Ii, aacA4, aacA7, aad9, aadA, aadA14, aadA2, aadA21, aadA24, aadA7, aadB, aadD, aadK, ant(4′)-IIb, ant(6)-Ia, aph(2″)-Ib, aph(2″)-Id, aph(3′)-Ia, aph(3′)-Ic, aph(3′)-IIa, aph(3′)-III, aph(3′)-IV, kac, ksgA, sat2A, sat4A, spc, strA, strB, streptomycin-3-kinase. | n = 39 |
| Beta-Lactam | |
| ampR, bla1, bla2, blaB-13, blaB-2, blaCARB-1, blaCARB-2, blaCARB-4, blaCMY-1, blaCMY-2, blaCTX-M-1, blaCTX-M-12, blaDHA-1, blaFOX-2, blaIMP-2, blaIMP-4, blaKPC-3, blaL2, blaOXA-1, blaOXA-2, blaOXA-7, blaOXA-9, blaOXA-26, blaOXA-27, blaOXA-61, blaOXY-2–2, blaPER-2, blaROB-1, blaSHV-1, blaSHV-37, blaSHV-44, blaSME-1, blaSME-2, blaSME-3, blaTEM-1A, blaTEM-1B, blaTEM-116, blaVIM-2, blaZ, ccrA, ccrB, ddcA, mecA, mecI, pbp-1A, pbp3r, pbp5, pbpX, penA. | n = 49 |
| Fluoroquinolone | |
| acrR, cme, cmeA, cmeB, cmeC, cmeR, cmr, emrA, emrB, mar, oqxA, oqxB, qnrA1, qnrB1, qnrB4, qnrD, qnrS1, qnrS2, | n = 18 |
| Lincosamide | |
| carA, lmrA, lmrB, lnuA, lnuB. | n = 5 |
| Macrolide | |
| ereA, ereB, ermA, ermAM, ermB, ermC, ermD, ermF, ermG, ermQ, ermT, ermX, ermY, lsaB, mefA, mphA, mphB, mphC, mreA, msrA, msrC, smpA, srmB, stpA, tlrC, ybit. | n = 26 |
| Miscellaneous | |
| albA, ank, arr3, bcrR, ble, colE1, emtA, erfA, erfB, mdfA, mmr, mupR, nimA, nimB, nonR, norA, oleB, oleC, res, vph. | n = 20 |
| Mobile Element | |
| int1(2), int1(3), int1(3′-CS), int2, int2_TnsA, int3, int3_repC, IS1182, IS150, pAD1, pAM alpha 1, pBR322, pMMB66EH, pSLT, RP4 IncP, Tn925, tnpA, tnpM, trans, trans1. | n = 20 |
| Phenicol | |
| cat, cat(pC194), cat(pC221), cat86, catA1, catA2, catA3, catB, catB2, catP, catQ, catS, cfr, cmlA1, cmlV, fexA, floR. | n = 17 |
| Quaternary Ammonium | |
| qacEdelta1, qacJ, smr. | n = 3 |
| Streptogramin B | |
| msrD, vatA, vatB, vatC, vatD, vatE, vatF, vgaA, vgbA, vgbB. | n = 10 |
| Sulfonamide | |
| sul1, sul2, sul3, sulI. | n = 4 |
| Tetracycline | |
| otrA, otrC, tcr, tet31, tet32, tet33, tet34, tet35, tet36, tet37, tet38, tet39, tetA, tetAP, tetB, tetBP, tetC, tetD, tetE, tetG, tetH, tetJ, tetK, tetL, tetM, tetO, tetQ, tetR, tetS, tetT, tetU, tetV, tetW, tetX, tetY, tetZ. | n = 36 |
| Trimethoprim | |
| dfrA1, dfrA5, dfrA7, dfrA8, dfrA9, dfrA12, dfrA13, dfrA15, dfrA20, dfrC, dfrD. | n = 11 |
| Vancomycin | |
| ddlA, vanA-A, vanA-Ao2, vanA-B, vanA-C, vanA-D, vanA-G, vanE, vanH-A, vanH-D, vanR-A, vanS-A, vanX-A, vanY-A, vanY-D, vanZ-A | n = 16 |