Fig. 5. Mlkl gene deficiency suppresses necroptosis and NET-related signaling pathways during thrombus formation.

From the left panel, TUNEL, Ly6b, RIPK3, CitH3, and F4/80 staining. a Representative figures of IVC-ligated wild-type mice and b IVC-ligated Mlkl^−/− mice (scale bar = 1 mm). Upper figures show the whole thrombus (scale bar = 1 mm) and lower figures show magnified image (scale bar = 250 μm). c Quantification of positive area of each staining. Data are mean ± SEM in each group. *p < 0.05 vs. respective control