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. 2018 Jul 25;8:11197. doi: 10.1038/s41598-018-29237-5

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Identification of tissue-enriched genes and prognostic genes. (A) Numbers of tissue-enriched genes in the 12 non-tumor tissue types. (B) Numbers of survival-related genes in the 16 cancer types. Genes with statistically significant differences (p < 0.05) by the Log-rank test were considered as survival-related genes with a median as cut-off value. (C) Venn diagrams showing number of tissue-enriched genes and prognostic genes and their overlap in different cancer types. The percentage of prognostic genes in liver-enriched genes is shown in parentheses.