Table 2.
Serum microbiome composition at the class level (25 most common OTUs)
| Young adults | Older adults | p value for group | |
|---|---|---|---|
| Firmicutes_Clostridia | 34.8 ± 14.3 | 34.5 ± 15.4 | 0.932 |
| Bacteroidetes_Bacteroidia | 18.2 ± 4.7 | 13.6 ± 5.0 | 0.003* |
| Firmicutes_Bacilli | 12.5 ± 7.0 | 11.4 ± 4.7 | 0.831 |
| Proteobacteria_Gammaproteobacteria | 9.6 ± 6.3 | 7.7 ± 3.2 | 0.580 |
| Actinobacteria_Actinobacteria | 4.9 ± 6.4 | 7.6 ± 7.4 | 0.093 |
| Firmicutes_Erysipelotrichi | 2.3 ± 1.6 | 8.6 ± 13.4 | 0.023 |
| Fusobacteria_Fusobacteriia | 5.9 ± 4.6 | 3.4 ± 3.6 | 0.035 |
| Proteobacteria_Betaproteobacteria | 2.7 ± 0.9 | 3.4 ± 2.3 | 0.496 |
| Proteobacteria_Alphaproteobacteria | 2.3 ± 2.3 | 2.4 ± 1.8 | 0.702 |
| Verrucomicrobia_Verrucomicrobiae | 1.9 ± 0.8 | 2.3 ± 1.3 | 0.217 |
| Proteobacteria_Epsilonproteobacteria | 0.8 ± 0.4 | 0.6 ± 0.4 | 0.085 |
| Actinobacteria_Coriobacteriia | 0.5 ± 0.2 | 0.6 ± 0.3 | 0.120 |
| Bacteroidetes_Flavobacteriia | 0.5 ± 0.2 | 0.6 ± 0.7 | 0.898 |
| Cyanobacteria_Chloroplast | 0.5 ± 0.4 | 0.7 ± 0.5 | 0.173 |
| Tenericutes_Mollicutes | 0.7 ± 0.5 | 0.5 ± 0.4 | 0.003* |
| Proteobacteria_Deltaproteobacteria | 0.4 ± 0.3 | 0.4 ± 0.3 | 0.865 |
| Bacteria_Other_Other | 0.3 ± 0.2 | 0.2 ± 0.2 | 0.004* |
| Bacteria_SR1_unknown | 0.2 ± 0.2 | 0.1 ± 0.2 | 0.016 |
| Bacteroidetes_Cytophagia | 0.04 ± 0.04 | 0.25 ± 0.49 | 0.003* |
| Cyanobacteria_Synechococcophycideae | 0.07 ± 0.04 | 0.16 ± 0.22 | 0.328 |
| Deferribacteres_Deferribacteres | 0.10 ± 0.10 | 0.10 ± 0.08 | 0.686 |
| Firmicutes_Other | 0.11 ± 0.07 | 0.06 ± 0.05 | 0.011* |
| Spirochaetes_Leptospirae | 0.10 ± 0.08 | 0.04 ± 0.06 | 0.001* |
| Actinobacteria_Acidimicrobiia | 0.03 ± 0.03 | 0.04 ± 0.06 | 0.045 |
| Cyanobacteria_Oscillatoriophycideae | 0.02 ± 0.03 | 0.10 ± 0.20 | 0.034 |
All values (mean ± SD) indicate relative abundance (%)
*Statistically significant after correction for false discovery rate