Table 2.

Multivariate logistic regression for the association between dementia and comorbidities for patients aged ≥ 45 years with diagnoses of AF (n = 11,209) in primary care attending the 75 PHCCs between January 1, 2001 and December 31, 2007

Number of patients	Men			Women
	All	< 75 years	≥ 75 years	All	< 75 years	≥ 75 years
	N = 6273	N = 3578	N = 2695	N = 4936	N = 1842	N = 3094
	OR (95% CI)	OR (95% CI)	OR (95% CI)	OR (95% CI)	OR (95% CI)	OR (95% CI)
Diagnosis
Hypertension	0.91 (0.72–1.14)	0.90 (0.57–1.44)	0.89 (0.68–1.15)	0.73 (0.60–0.90)	0.64 (0.35–1.16)	0.74 (0.60–0.92)
Coronary heart disease	1.13 (0.89–1.45)	1.16 (0.69–1.93)	1.09 (0.83–1.43)	0.87 (0.70–1.10)	0.67 (0.31–1.46)	0.89 (0.70–1.13)
Congestive heart failure	1.27 (1.01–1.61)	1.49 (0.93–2.37)	1.20 (0.92–1.57)	1.43 (1.15–1.76)	1.30 (0.71–2.39)	1.40 (1.12–1.76)
Cerebrovascular diseases	1.82 (1.43–2.31)	2.76 (1.71–4.44)	1.56 (1.18–2.05)	1.11 (0.89–1.39)	2.08 (1.08–4.01)	1.04 (0.82–1.32)
Obesity	0.54 (0.23–1.25)	0.14 (0.02–1.06)	1.02 (0.40–2.63)	0.54 (0.26–1.12)	0.62 (0.18–2.12)	0.48 (0.19–1.20)
Diabetes mellitus	1.18 (0.92–1.52)	1.40 (0.87–2.27)	1.07 (0.80–1.44)	1.05 (0.85–1.29)	1.15 (0.63–2.10)	1.05 (0.84–1.31)
COPD	0.68 (0.47–1.00)	0.58 (0.23–1.47)	0.71 (0.47–1.09)	1.09 (0.81–1.46)	1.81 (0.87–3.74)	0.98 (0.70–1.35)
Depression	2.04 (1.41–2.94)	2.81 (1.48–5.37)	1.72 (1.10–2.68)	1.38 (1.03–1.85)	1.78 (0.82–3.86)	1.33 (0.97–1.83)
Anxiety	1.33 (0.72–2.42)	2.02 (0.69–5.89)	1.21 (0.59–2.48)	1.33 (0.88–1.99)	1.64 (0.58–4.61)	1.26 (0.81–1.96)

Models are adjusted for age, socioeconomic factors, and all comorbidities. Information on educational level and marital status is missing for some individuals. Italicized values are statistically significant